Abstract: AlphaFold3 is a state-of-the-art deep learning model for biomolecular structure prediction, introducing architectural changes and expanded input diversity beyond AlphaFold2. These ...

The three-dimensional structure of a protein underpins its biological function, making structure determination and prediction central challenges in structural biology. Although experimental techniques ...

Imagine an official in India facing a public health crisis, say a new variant of the often-deadly Nipah virus cropping up in clinics. A new vaccine could help to contain the outbreak, but developing ...

Nearly two years after Google DeepMind released an updated AlphaFold3 geared at drug discovery, its biopharmaceuticals spin-off, Isomorphic Labs, announced an even more powerful ...

Previously discovered large RNA polymerase ribozyme structure (grey, based on pdb: 8T2P) vs. newly discovered small RNA polymerase ribozyme QT45 (blue, AlphaFold3 prediction). Credit: MRC Laboratory ...

According to the RNA world hypothesis, life began when RNA molecules evolved the ability to make more copies of themselves. Now we have discovered an RNA molecule that is almost capable of this – it ...

The research team defines Protenix as a comprehensive AF3 reproduction. It re-implements the AF3-style diffusion architecture for all-atom complexes and exposes it in a trainable PyTorch codebase.

Scientists have cracked a key mystery behind spider silk’s legendary strength and flexibility. They discovered that tiny molecular interactions act like natural glue, holding silk proteins together as ...

Join ACRL from 1:00 – 2:00 p.m. Central on Thursday, January 22 for the Online Learning webcast “Making Great Video Tutorials: Best Practices and Practical Planning.” This webinar offers a practical, ...

This figure highlights four main modules: (1) Molecular & Computational Frontiers, represented by AlphaFold3 protein structure prediction (precision diagnostics), GeneCompass federated learning, and ...