RNA sequencing (RNA-seq) is a powerful transcriptomics approach for measuring differential gene expression (DGE) across the ...

Introducing a new RNA-seq platform for intracellular multimodal profiling that could transform cancer research and ...

A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the earliest stages of ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...

Researchers at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), led by Prof. Gracjan Michlewski, ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Cas12a2, an RNA-triggered system that selectively kills cancer and virus-infected cells by inducing extensive DNA damage ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

Understand the stages of a standard RNA-seq bioinformatics workflow, including the role of QC, alignment, gene expression quantification, and specialized application analyses Identify key QC metrics ...

While bulk sequencing quickly became the preferred method, scRNA-seq has increased in popularity in the last decade. In 2015, just 6 % of RNA-seq papers used single-cell methodologies. By 2025, the ...